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Clindamycin Hcl-An Overview
| November 19, 2011 | Posted by admin under Clindamycin, Medication Guide |
Clindamycin HCL which is also better known as Clindamycin Hydrochloride it a drug that is prescribed as an antibiotic and is used to treat bacterial infections of different kinds. It comes as an oral capsule. Though Clindamycin is a generic name, the product is available in different brand names. Generic forms of this antibiotic are also available in the market. Oral Clindamycin HCL is very commonly used for the treatment of different types of respiratory infection, infections of the abdomen and also various types of infections to the outer skin and also soft tissues. There have also been instances where the drug has been used as a veterinary product and also has been used before any dental related jobs to prevent heart attacks from happening. It has been found that heart attacks occur when a person is under dental care. Let us now over the next few lines try and find out more information about the products, particularly with regard to its functions, types, side effects and other such related matters.
As is the case with most antibiotics Clindamycin HCL also works to stop infections that are caused by anaerobic bacteria. By the way, anaerobic bacteria are those that can survive without the presence of oxygen. There are quite a few types of such bacteria and a few examples could be Streptopcoccus pneumonia and Staphylococcus aureus. This drug works by retarding or inhibiting the manufacture of protein by the bacteria. Once the bacteria are deprived of oxygen, they will not be able to replicate and multiply in the body and therefore the infection that is caused by the bacteria can be controlled and reversed. This is a very simple but extremely effective method in which the drug works to treat various kinds of infections.
As explained earlier, there are many different types and brands of Clindamycin and let us look at a few of them. The most common brand names are Cleocin which is manufactured and market by Pfizer. Then there are also other brands such as Dalacin and Clinacin coming from the houses of Upjohn and Invert. However, Clinacin is a drug that is used only for veterinary purposes and is not recommended for human use. The generic forms of this drug are also available and the dosages range from 75 mg to 300 mg. The drug is also available in topical and intravenous forms. However the topical and intravenous forms contain Clindamycin Phosphate and they do not contain Clindamycin HCL.
As is the case with most of the antibiotic drugs this particular drug has also it’s own share of problems. This is a widespread concern that unregulated and unmonitored use of Clindamycin HCL has resulted in many patient suffering with antibiotic induced diarrhea. This happens because while the patient is on treatment with this drug a new group of bacteria by the name Clostridium Difficile grows in the patient. This bacteria is also known as C diff. This happens because during the period when Clindamycin HCL is used, many digestive enzymes and bacteria get killed but C diff thrives and grows. While the body helps a check of C diff in the normal course, during treatment with this drug the balance gets affected leading to a proliferation of C diff which causes mild to severe forms of colitis. The toxins that are released from C diff can cause abdominal cramps, bloating of the stomach and ultimately could lead to diarrhea or colitis. Hence, the patients who have had a history of abdominal problems such as cramps and diarrhea should be very carefully evaluated and monitored before being administered this drug.
There are quite a few side effects related with this disease, and it could range from mild stomach upset to nausea. Diarrhea in various forms has also been reported because of the use of this drug. However, most of the time the symptoms can be managed in the home itself and very rarely medical intervention is required. However, in case the patient shows symptoms of severity such as blood in the stool or severe abdominal cramps, in such cases it is very important to immediately discontinue the medication and put the patient on various tests and examinations to rule out the infection from C diff. But on the whole, this medicine is very well tolerated and whatever mild side effects that could arise disappear within a few days.
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